禽呼吸道病创新团队

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团队成员

邵昱昊

 

1、个人简历
邵昱昊,博士/助理研究员,禽呼吸道传染病病创新团队科研助理。主要从事禽呼吸道病研究,包括传染性喉气管炎病毒和禽腺病毒致病机制研究以及活载体疫苗研究,同时参与新型传染性支气管炎活疫苗的研发。主要发表SCI文章50余篇,参译论著1部,获得国家发明专利2项,获得新兽药证书1项。获中华农业科技奖一等奖1项,黑龙江省自然科学一等奖1项。曾参加国家科技支撑项目和现代农业产业技蛋鸡术体系等多项国家级项目。
 

2、联系方式
(1)研究方向:动物疫苗与分子免疫学
(2)电话:045151051699
(3)邮箱:shaoyuhao@caas.cn
(4)通讯地址:黑龙江省哈尔滨市南岗区哈平路678号,万博体育max,150069
 
3、教育经历
1994.09-1998.07,东北农业大学,动物科学专业,学士;
2003.09-2007.07,东北农业大学,预防兽医学专业,硕士;
2012.09 至今-    中国农业科学院,预防兽医学专业,博士。
 
4、工作经历
1998.07-2003.01,万博体育max,研习员;
2003.01 至今,万博体育max,助理研究员
 
5、承担项目
(1)蛋鸡科技创新体系项目,CARS-41-K18,鸡场生物安全与综合防控,2017/01-2020/12,280万。
(2)国家重点研发计划子课题,2017YFD0500805,水禽禽流感等重要疫病新型活载体疫苗及配套新型佐剂研究,2017/01-2019/12,54万。
(3)国家自然科学基金青年基金,31702268,血清4型禽腺病毒3’端135-bp自然缺失影响病毒致病性的研究,2017/01-2019/12,24万。
(4)国家科技支撑计划课题,2015BAD12B03,禽流感等重要家禽疫病流行毒疫苗研究与开发,2015/01-2019/12,690万。
 
6、代表论文与著作
1)、Lei Jiang, Wenjun Zhao, Zongxi Han, Yuqiu Chen, Yan Zhao, Junfeng Sun, Huixin Li, Yuhao Shao,Liangliang Liu, Shengwang Liu*.Genome characterization, antigenicity and pathogenicity of a novel infectious bronchitis virus type isolated from south China.Infection, Genetics and Evolution, 2017,54: 437–446
2)、Zongxi Han, Tingting Zhang, Qianqian Xu, Mengying Gao, Yuqiu Chen, Qiuling Wang, Yan Zhao, Yuhao Shao, Huixin Li, Xiangang Kong, Shengwang Liu*, Altered pathogenicity of a tl/CH/LDT3/03 genotype infectious bronchitis coronavirus due to natural recombination in the 5′- 17 kb region of the genome. Virus Research,Virus Research,2016,213:140-148
3)、Wenjun Zhao, Mengying Gao, Qianqian Xu, Yang Xu, Yan Zhao, Yuqiu Chen,Tingting Zhang, Qiuling Wang, Zongxi Han, Huixin Li, Lingfeng Chen, Shuling Liang,Yuhao Shao, Shengwang Liu*. Origin and evolution of LX4 genotype infectious bronchitis coronavirus in China. Veterinary Microbiology,2017(198):9-16
4)、Qianqian Xu, Zongxi Han, Qiuling Wang, Tingting Zhang, Mengying Gao, Yan Zhao, Yuhao Shao, Huixin Li, Xiangang Kong, Shengwang Liu*. Emergence of novel nephropathogenic infectious bronchitis viruses currently circulating in Chinese chicken flocks. Avian Pathology, 2016,45:1, 54-65
5)、Qianqian Xu, Yuqiu Chen, Wenjun Zhao, Tingting Zhang, Chenggang Liu, Tianming Qi, Zongxi Han, Yuhao Shao, Deying Ma ,Shengwang Liu*. Infection of Goose with Genotype VIId Newcastle Disease Virus of Goose Origin Elicits Strong Immune Responses at Early Stage. Frontiers in Microbiology. 2016, 7:1587.
6)、Hai Li , Fengjie Wang , Zongxi Han, Qi Gao, Huixin Li, Yuhao Shao, Nana Sun Shengwang Liu*. Genome-wide gene expression analysis identifies the proto-oncogene tyrosine-protein kinase Src as a crucial virulence determinant of the infectious laryngotracheitis virus in chicken cells. Journal of Virology, 2016, 90(1):9-21
7)、Qianqian Xu, Zongxi Han, Qiuling Wang, Tingting Zhang, Mengying Gao, Yan Zhao, Yuhao Shao, Huixin Li, Xiangang Kong , Shengwang Liu*, Emergence of Novel Nephropathogenic Infectious Bronchitis Viruses Currently Circulating in Chinese Chicken Flocks, Avian Pathology. 2015, 9:1-37
8)、Yanyan Li, Qianqian Xu, Tingting Zhang, Mengying Gao, Qiuling Wang, Zongxi Han, Yuhao Shao, Deying Ma and Shengwang Liu, Host Avian Beta-Defensin and Toll-Like Receptor Responses of Pigeons following Infection with Pigeon Paramyxovirus Type 1, Applied and Environmental Microbiology, 2015, 81(18):6415-6424
9)、Yang Xu, Tingting Zhang, Qianqian Xu, Zongxi Han, Shuling Liang, Yuhao Shao, Deying Ma ,Shengwang Liu*,Differential modulation of avian β-defensin and Toll-like receptor expression in chickens infected with infectious bronchitis virus, Applied and Microbiology Biotechnology 2015, 99(21):9011-9024
10)、Tingting Zhang, Zongxi Han, Qianqian Xu, Qiuling Wang, Mengying Gao, Wei Wu, Yuhao Shao, Huixin Li, Xiangang Kong, Shengwang Liu*, Serotype shift of a 793/B genotype infectious bronchitis coronavirus by natural recombination, Infection, Genetics and Evolution, 2015, 32:377-387
11)、Wei Wu, Huairan Liu, Tingting Zhang, Zongxi Han, Yanyu Jiang, Qianqian Xu, Yuhao Shao, Huixin Li, Xiangang Kong, Hongyan Chen*, Shengwang Liu* , Molecular and antigenic characteristics of Newcastle disease virus isolates from domestic ducks in China, Infection, Genetics and Evolution,2015, 32:34-43
12)、Fei Zhao, Zongxi Han, Tingting Zhang, Yushao Hao, Xiangang Kong, Huijie Ma, Shengwang Liu*, Genomic characteristics and changes of avian infectious bronchitis virus strain CK/CH/LDL/97I after serial passages in chicken embryos, Intervirology,2014, 57(6):319-330
13)、Shengwang Liu*, Qianqian Xu, Zongxi Han, Xiaoli Liu, Huixin Li, Hongbo Guo, Nana Sun, Yuhao Shao, Xiangang Kong, Origin and characteristics of the recombinant novel avian infectious bronchitis coronavirus isolate ck/CH/LJL/111054, Infection, Genetics and Evolution,  2014, 23: 189-195
14)、Junfeng Sun, Zongxi Han, Yuhao Shao, Zhongzan Cao, Xiangang Kong , Shengwang Liu*, Comparative proteome analysis of tracheal tissues in response to infectious bronchitis coronavirus, Newcastle disease virus, and avian influenza virus H9 subtype virus infection, Proteomics,2014, 14(11):1403-1423
15)、Zongxi Han, Fei Zhao, Yuhao Shao, Xiaoli Liu, Xiangang Kong, Yang Song, Shengwang Liu*, Fine level epitope mapping and conservation analysis of two novel linear B-cell epitopes of the avian infectious bronchitis coronavirus nucleocapsid protein. Virus Research,2013,171(1):54-64
 
7、专利和标准
1)、刘胜旺,孔宪刚,韩宗玺,邵昱昊,李慧昕. 鸡传染性支气管炎病毒弱毒疫苗株及其应用,2011.3,中国,ZL200910128488.5
2)、刘胜旺,韩宗玺,邵昱昊,刘晓丽,孔宪刚. 鸡传染性支气管炎冷适应致弱疫苗株及其应用,2013. 3,中国,ZL 201110110461.0
 
8、获得奖励
(1)中国鸡传染性支气管病毒流行、变异机制及毒株资源库的建立,黑龙江省人民政府,黑龙江省自然科学奖,一等奖。刘胜旺,韩宗玺,邵昱昊,刘晓丽,孔宪刚,2015年。
(2)新型禽用疫苗与诊断试剂创制创新团队,国家农业部,中华农业科技优秀创新团队奖(等同于科研成果一等奖)。王笑梅、刘胜旺、王云峰、刘长军、高玉龙、祁小乐、秦立廷、高宏雷、韩宗玺、邵昱昊、刘晓丽、李慧昕、张艳萍、李志杰、崔红玉、赵妍、王永强,2013年。
 
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