动物病原结构与生物信息研究创新团队

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首席

1、个人简历

王靖飞,男,博士,研究员,万博体育max、东北农业大学兽医专业硕士生导师,动物病原结构与生物信息研究创新团队首席科学家,国家动物疫病数据中心副主任,中国畜牧兽医学会信息技术分会副理事长,中国农业部/FAO“中国兽医现场流行病学培训项目(FETPV)”导师,中国畜牧兽医学会高级会员。在国内外杂志发表研究论文50余篇;出版专著4部;注册软件5部;获省部级奖励5项;主持课题10余项。目前主要从事基于冷冻电镜的动物病毒结构解析、病毒基因组学分析及动物疫病流行趋势建模等相关研究。
 
2、联系方式
(1)研究方向:动物传染病及其病原分子流行病学
(2)电话:0451-51051770
(3)邮箱:wangjingfei@caas.cn
(4)通讯地址:黑龙江省哈尔滨市香坊区哈平路678号,150069
 
3、教育经历 
1992.09-1996.06  甘肃农业大学 兽医专业 农学学士
1996.09-1999.06  甘肃农业大学 兽医专业 农学硕士
1999.09-2002.06  东北农业大学 兽医专业 农学博士
 
4、工作经历
2002–2004  万博体育max 助理研究员
2004–2013  万博体育max 副研究员
2013–今      万博体育max 研究员
 
5、承担项目
(1)“十三五” 国家重点研发计划项目:猪病未知病原识别技术研究(2016YFD0500705,2016.07-2020.12),150万元;
(2)“十三五” 国家重点研发计划项目:畜禽重要疫病流行病学数据库和传播风险评估模型构建(2017YFD0500105,2017.07-2020.12),74万元;
(3)“十三五” 国家重点研发计划项目:重大动物源性病原体传入风险评估和预警技术研究(2017YFC1200502,2017.07-2020.06),142万元。
 
6、代表论文与著作
(1) Mingxia Sun, Linlin Hou, Yan-dong Tang, Yonggang Liu, Shujie Wang, Jingfei Wang, Nan Shen, Tongqing An, Zhijun Tian, Xuehui Cai. Pseudorabies virus infection inhibits autophagy in permissive cells in vitro. Scientific Reports, 2017, 7: 39964.
(2) Yongqiang Wang, Yulu Duan, Chunyan Han, Shuai Yao, Xiaole Qi, Yulong Gao, Helena J. Maier, Paul Britton, Lei Chen, Lizhou Zhang, Li Gao, Honglei Gao, Nan Shen, Jingfei Wang, Xiaomei Wang. Infectious Bursal Disease Virus Subverts Autophagic Vacuoles to Promote Viral Maturation and Release. J Virol. 2017, 14, 91(5). doi: 10.1128/JVI.01883-16. 
(3) Jingfei Wang, Huiqiang Wen, Shida Wang, Wei Sun, Nan Shen, Zaisi Liu, Yimin Liu, Yonggang Liu, Chenggang Jiang, Gang Sun, Flavie Goutard, Xuehui Cai. Preliminary study on prevalence, risk factor, and genetic homogeneity of porcine reproductive and respiratory syndrome virus in registered pig farms in Heilongjiang, China. Transboundary and Emerging Diseases, 2015, doi: 10.1111/tbed.12312. 
(4) Jingfei Wang, Miao Wang, Shida Wang, Zaisi Liu, Nan Shen, Wei Si, Gang Sun, Julian A. Drewe, Xuehui Cai. Peste des Petits Ruminants Virus in Heilongjiang province, China, 2014. Emerging infectious diseases, 2015, 21(4):677-680.
(5) Qi Wang, Xiaofei Li, Xiaolin Ji, Jingfei Wang, Nan Shen, Yulong Gao, Xiaole Qi, Yongqiang Wang, Honglei Gao, Shide Zhang, Xiaomei Wang. A Recombinant Avian Leukosis Virus Subgroup J for Directly Monitoring Viral Infection and the Selection of Neutralizing Antibodies. PLoS ONE, 2014,DOI:10.1371/journal.pone.0115422.
(6) Ronghong Hua*, Yenan Li, Zhenshi Chen, Like Liu, Hong Huo, Xiaolei Wang, Liping Guo, Nanshen, Jingfei Wang, Zhigao Bu. Generation and characterization of a new mammalian cell line continuously expressing virus-like particles of Japanese encephalitis virus for a subunit vaccine candidate. BMC Biotechnology 2014, 14:62
(7) Yan Chen, Jian Zhang, Chuanling Qiao, Jingfei Wang, Huanliang Yang, Hualan Chen*. Identification of a linear epitope on the haemagglutinin protein of pandemic A/H1N1 2009 influenza virus using monoclonal antibodies. Archives of Virology. 2014, 159(6): 1413-1419. DOI 10.1007/s00705-013-1955-5.
(8) Te Liang, Decheng Yang, Mengmeng Liu, Chao Sun, Fang Wang, Jingfei Wang, Haiwei Wang, Shanshan Song, Guohui Zhou, Li Yu*. Selection and characterization of an acid-resistant mutant of serotype O foot-and-mouth disease virus, Archives of Virology, 2014, 159: 657-667.
(9) Yingying Cong, Dante S. Zarlenga, Juergen A, Richt, Xin Wang, Yang Wang, Siqingaowa Suo, Jingfei Wang, Yudong Ren, Xiaofeng Ren. Evolution and homologous recombination of the hemagglutinin-esterase gene sequences from porcine torovirus. Virus Genes. 2013, 47 (1):66-74. doi: 10.1007/s11262-013-0926-y. 
(10) Ding Zhang, Caifeng Chen, Binbin Zhao, Lulu Gong, Wenjing Jin, Jingjun Liu, Jingfei Wang, Tiantian Wang, Xiaohui Yuan, Youwen He. A novel antibody humanization method based on epitopes scanning and molecular dynamics simulation. PLoS ONE, 2013,8(11):e80636
(11) Zheng Chai, Haiwei Wang, Guohui Zhou, Decheng Yang, Jingfei Wang, Li Yu*. Adenovirus-vectored type Asia1 foot-and-mouth disease virus (FMDV) capsid proteins as a vehicle to display a conserved, neutralising epitope of type O FMDV, Journal of Virological Methods, 2013, 188(1-2): 175-182.
(12) Xiaohui Yuan, Yingchen Wang, Wenjing Jin, Binbin Zhao, Caifeng Chen, Jian Yang, Jingfei Wang, Yingying Guo, Jingjun Liu, Ding Zhang, Lulu Gong, Youwen He*. Structure-Based High-Throughput Epitope Analysis of Hexon Proteins in B and C Species Human Adenoviruses (HAdVs), PLoS ONE, 2012, 7(3): e32938.
(13) Yanxia Hou, Yingying Guo, Chunyan Wu, Nan Shen, Yongping Jiang, Jingfei Wang*. Prediction and identification of T cell epitopes in the H5N1 influenza virus nucleoprotein in chicken, PLoS ONE, 2012, 7(6): e39344.
(14) Hualan Chen, Zhigao Bu, Jingfei Wang. Epideimology and Control of H5N1 Avian Influenza in China. Avian Influenza. MonogrViro. Basel, Karger, 2008, 27: 27-40.
(15) 《兽医微生物学》,中国农业出版社,2013,参编。
 
7、专利和标准
(1) 王靖飞,禽流行病学数据库管理系统V1.0,2015SR038915.
(2) 王靖飞,序列熵值计算软件[简称:Entropy] V1.0.0,2009SR061228;
(3) 王靖飞,鸡疾病诊断数字化智能系统(B/S),2005SR08613;
(4) 王靖飞,鸡疾病防治数字化智能系统(B/S),2005SR08612;
(5) 王靖飞,中国禽流感毒株信息管理系统,2004SR09023;
 
8、获得奖励
(1) 动物疫病风险评估方法的建立及应用,黑龙江省畜牧科技一等奖,第二完成人,2010年; 
(2) 动物疫病风险评估方法的建立及应用,黑龙江省科技进步二等奖,第二完成人,2010年;
(3) 猪瘟、猪繁殖与呼吸综合征、猪伪狂犬病毒抗体三种金标快速检测试纸条等的研制及初步应用,黑龙江省科技进步三等奖,第六完成人,2010年;
(4) 猪瘟、猪繁殖与呼吸综合征、猪伪狂犬病毒抗体三种金标快速检测试纸条等的研制及初步应用,哈尔滨市科技进步二等奖,第六完成人,2009年;
(5) 猪禽等几种重大传染病胶体金快速诊断试纸条的研制,中国农业科学院科学技术成果二等奖,第六完成人,2006年。
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